cAMP-dependent protein kinase

cAMP-dependent protein kinase (PKA) is a serine/threonine kinase with catalytic (protein phosphorylating) activity that is modulated by cAMP levels. Specific protein kinases transfer a phosphate group from a donor such as ATP to amino acid acceptors in proteins, while protein phosphatases remove the phosphate groups that have been attached by protein kinases.

PKA is highly conserved with receptor tyrosine kinases.