Enzymes, proteins, riboproteins and signaling pathways.

IκB kinase

Activation of IκB kinase (IKK) by stress signals stimulates phosphorylation of two serine residues in the regulatory domain 0f Inhibitor of kappa B (IκB), targetting the IκB molecules for ubiquitin/proteasome degradation, and releasing NF-κB from inhibition. (Intact Inhibitor of kappa B (IκB) inactivates NF-κB by sequestering NF-κB dimers within the cytoplasm.) Physiological activities mediated by NF-κB include cellular proliferation, and inflammatory, immune, and cellular survival responses.

. . . catalyzing since 10/06/06
Search WWW Search enzymatics.blogspot.com Search signaling-receptor.blogspot.com Search chemistryolife.blogspot.com Search krebbing.blogspot.com Search cellular-immunity.blogspot.com Search biopoiesis.blogspot.com Search phototroph.blogspot.com Search endosymbionts.blogspot.com